Aripiprazole and Hair Loss: Does Abilify Help or Hurt Your Hair?
You came here asking if aripiprazole (Abilify) can treat hair loss. Short answer: it doesn’t treat common medical hair loss like male/female pattern hair loss or alopecia areata. In rare cases, it can even trigger shedding. The one real exception? If hair is missing because of hair-pulling disorder (trichotillomania), aripiprazole may help reduce pulling, and hair regrows as a result. That’s a different problem than the follicles failing. So the goal here is simple: help you tell which type of hair loss you have, what aripiprazole can and can’t do, what to try instead that actually works, and how to talk to your doctor with a plan.
TL;DR
- Aripiprazole is not a treatment for androgenetic alopecia (pattern baldness) or alopecia areata.
- It has a rare side effect of drug-induced shedding (telogen effluvium) reported in case reports.
- It can help trichotillomania (hair-pulling) in some people; hair regrowth then follows from not pulling.
- For pattern hair loss, proven options are minoxidil, finasteride/dutasteride (men), spironolactone (women), low-level laser, microneedling, PRP, and for alopecia areata, JAK inhibitors (where approved).
- If your shedding started 1-3 months after starting or changing a psych med, talk to your prescriber; it may be reversible.
What the evidence actually says about aripiprazole and hair
Let’s separate three problems that get muddled online: pattern hair loss (androgenetic alopecia), autoimmune patchy loss (alopecia areata), and hair loss from pulling (trichotillomania). These are different conditions with different fixes.
Pattern hair loss is follicle miniaturisation driven by hormones and genetics. Aripiprazole doesn’t affect that biology. Large reviews of hair loss treatments point to minoxidil and finasteride as the mainstays for men, with minoxidil and anti-androgens for women. A landmark network meta-analysis in JAMA Dermatology (2015) compared finasteride and minoxidil and found both effective in androgenetic alopecia. Aripiprazole doesn’t feature because it has no role.
Alopecia areata is autoimmune. In the UK and EU, baricitinib received approval for severe cases in 2022, and ritlecitinib was recommended by NICE in 2024 for some patients with severe disease. Again, aripiprazole is not an immune modulator used here.
Trichotillomania is different: hair is removed by repetitive pulling. Reduce the pulling, and follicles usually grow hair back. Here, aripiprazole might help-not by feeding follicles, but by dialling down the urge to pull. Evidence comes from small open-label studies and case series-think tiny samples, no placebo, but consistent signals. Case series in Journal of Clinical Psychopharmacology (2008-2013) reported improvements in hair-pulling severity with low-dose aripiprazole (often 2-10 mg/day). A 2013 Cochrane Review on trichotillomania pharmacotherapy concluded evidence for medications is limited and mixed overall, but antipsychotic augmentation (including aripiprazole) shows promise in select cases. Behavioural therapy (habit reversal training) remains first-line; meds are add-ons when therapy isn’t enough.
Can aripiprazole cause hair loss? Rarely, yes. There are scattered case reports of telogen effluvium-diffuse shedding-after starting aripiprazole, with resolution after stopping or switching. Reviews on psychotropic-induced alopecia (Drug Safety, 2016; Expert Opinion on Drug Safety, 2015) list aripiprazole among agents with infrequent hair loss events. This kind of shedding typically kicks in 1-3 months after a trigger and often reverses a few months after fixing the trigger.
So where does that leave you? If your issue is pattern hair loss or alopecia areata, aripiprazole won’t help. If your missing hair is from pulling, it might-mainly by reducing urges-usually alongside therapy. If you started shedding a couple months after beginning aripiprazole (or changing the dose), it could be the culprit, and you should talk to your prescriber about options.

Risks, side effects, and who should (and shouldn’t) consider it
Aripiprazole is a partial dopamine D2 and serotonin 5‑HT1A agonist used for conditions like schizophrenia, bipolar disorder, and as an add‑on for depression. Using it solely for cosmetic hair concerns would be off‑label and, frankly, a mismatch of risk vs benefit.
Who might consider it? People with moderate to severe trichotillomania who have tried-but not fully responded to-behavioural therapy (habit reversal training/CBT) and have care through a psychiatrist. In the case series noted earlier, clinicians used low doses (commonly 2-10 mg/day) and titrated slowly. Gains usually show up in urges and pulling frequency within weeks; hair regrowth then follows the normal hair cycle over months. Remember: this is not a hair drug. It’s a psychiatric medication sometimes used to control a behaviour that damages hair.
Common side effects include restlessness (akathisia), insomnia or sleepiness, nausea, headache, and weight changes. Less common but important: metabolic shifts (glucose, lipids), movement disorders, and rare impulse‑control problems. Hair shedding is rare but reported. If you already have unexplained shedding, weigh this carefully with your clinician.
Red flags-situations where aripiprazole likely isn’t right for a hair concern:
- Pattern hair loss without any hair‑pulling behaviour.
- Patchy loss with exclamation‑mark hairs or nail pitting suggesting alopecia areata.
- Shedding that started after a new medication-especially if aripiprazole was that medication.
- No psychiatric indication for aripiprazole and no trichotillomania diagnosis.
UK‑specific note: off‑label prescribing for trichotillomania is specialist territory. If you’re in England, expect your GP to refer you to psychiatry or an OCD/related disorders service. Behavioural therapy (habit reversal training) is often available via IAPT/Local Talking Therapies services; ask for therapists with body‑focused repetitive behaviours experience.
Pregnancy and breastfeeding need extra caution. Pattern hair loss drugs like finasteride are not safe in pregnancy. Aripiprazole has its own risk profile-discuss family planning with your clinician before any changes.
Better routes for hair loss: decision guide, checklist, and data
Before chasing fixes, pin down the type of hair loss. Here’s a quick decision guide you can use with your GP or dermatologist.
- Map the pattern.
- Widening part, temple recession, crown thinning over years? Likely androgenetic alopecia.
- Smooth circular/oval patches that may regrow then recur? Think alopecia areata.
- Sudden diffuse shedding 1-3 months after stress, illness, childbirth, crash dieting, or a new med? Telogen effluvium.
- Broken hairs of different lengths, tingling/relief with pulling, tension building before pulling? Suspect trichotillomania.
- Check triggers and timeline.
- Did shedding start after starting/stopping a psych med, including aripiprazole? Note the month and dose.
- Any high fever/COVID‑19, surgery, iron deficiency, thyroid changes, major life stress in the past 3 months?
- Do basic tests (through your GP).
- Ferritin (iron stores), full blood count, TSH (thyroid), vitamin D, B12; consider zinc if diet is restricted.
- Pick evidence‑based treatments by type.
Evidence‑backed options to discuss, by condition:
- Androgenetic alopecia (men): topical minoxidil 5% once/twice daily; oral finasteride 1 mg/day; consider dutasteride (off‑label) if poor response; microneedling; low‑level laser devices; PRP injections. The 2015 JAMA Dermatology analysis supports minoxidil/finasteride; later meta‑analyses support microneedling and PRP as add‑ons.
- Androgenetic alopecia (women): topical minoxidil 2-5%; oral minoxidil low‑dose (off‑label) under specialist care; spironolactone (monitor potassium/blood pressure); consider low‑level laser and microneedling.
- Alopecia areata: intralesional corticosteroids for patches; for severe cases, JAK inhibitors like baricitinib (EU/UK approval 2022) and ritlecitinib (NICE 2024 recommendation) where eligible; topical immunotherapy in specialist clinics.
- Telogen effluvium: fix the trigger (iron deficiency, thyroid issues, medication, severe calorie deficit). Hair usually recovers over 3-6 months once the cause is handled. Gentle hair care; avoid crash diets.
- Trichotillomania: habit reversal training (HRT) is first‑line; add meds only if needed-N‑acetylcysteine has mixed evidence; small studies and case series support low‑dose aripiprazole in selected patients under psychiatric care.
Quick, practical checklist you can take to your appointment:
- Photos: take clear photos of your part, temples, and crown under the same light each month.
- Timeline: list new meds, illnesses, major stressors, diet changes in the last 6 months.
- Symptoms: itching, burning, broken hairs, nail pitting, eyebrow/eyelash changes.
- Family history: who in your family has hair loss and what type?
- Goals: slow shedding, regrow hair, fill patches, or stop pulling? These guide choices.
If your story still points to a medication trigger, here’s a simple rule of thumb: shedding that starts about 1-3 months after a new drug often suggests telogen effluvium. Don’t stop a prescribed med on your own-many times a dose change or a switch within the same class can help without losing control of your mental health. Your prescriber will balance risks and options.
How does aripiprazole stack up across hair problems? This summary helps set expectations.
Hair problem | Will aripiprazole help? | Evidence quality | Dose used in reports | Timeframe for hair change |
---|---|---|---|---|
Androgenetic alopecia (pattern loss) | No | None for efficacy | Not applicable | Not applicable |
Alopecia areata (autoimmune) | No | None for efficacy | Not applicable | Not applicable |
Telogen effluvium (drug‑induced shedding) | May worsen (rare side effect) | Case reports only | Variable; effect is idiosyncratic | Shedding often begins 1-3 months after start |
Trichotillomania (hair‑pulling) | Sometimes reduces pulling; indirect hair regrowth | Small open‑label studies and case series; limited | Often 2-10 mg/day in reports | Urge reduction in weeks; regrowth in months |
One more practical tip: whatever route you take, commit to 3-6 months before judging hair results. Hair cycles are slow. Track progress with photos and a simple weekly note on shedding and styling coverage.
Mini‑FAQ (quick answers you’re likely searching for):
Can aripiprazole cause hair loss? Rarely, yes. Case reports describe telogen effluvium after starting aripiprazole, with improvement after dose reduction or discontinuation.
Can aripiprazole grow hair? Not directly. It may help reduce hair‑pulling in trichotillomania; hair regrows because pulling stops.
What dose is used for trichotillomania? Studies are small and varied, but clinicians often try low doses (2-10 mg/day) as augmentation to therapy. This is specialist, off‑label care.
Is it safe to combine aripiprazole with minoxidil or finasteride? There’s no typical drug-drug interaction between these. That said, only your prescriber can confirm safety for you given your meds and health.
How long until I see hair back after stopping pulling? New growth may be visible in 6-12 weeks, with thicker coverage over 6-12 months, assuming follicles were not scarred.
What about N‑acetylcysteine (NAC) for trichotillomania? An adult RCT (2009) showed benefit; a paediatric RCT (2013) did not. It’s sometimes tried, typically alongside therapy.
What should I ask my GP or psychiatrist? Ask: Could my shedding be telogen effluvium from a medication change? What labs should we check? If I have trichotillomania, can I access habit reversal therapy and would low‑dose aripiprazole be appropriate?
Key sources to look up or discuss with your clinician:
- JAMA Dermatology (2015): network meta‑analysis on minoxidil and finasteride for androgenetic alopecia.
- Drug Safety (2016) and Expert Opinion on Drug Safety (2015): reviews of psychotropic‑induced alopecia.
- Journal of Clinical Psychopharmacology (2008-2013): open‑label aripiprazole studies/case series in trichotillomania.
- Cochrane Review (2013): pharmacotherapy for trichotillomania-limited evidence overall, behavioural therapy first‑line.
- British Association of Dermatologists/NICE (2022-2024): guidance and technology appraisals for alopecia areata treatments including JAK inhibitors.
Bottom line: if you’re weighing aripiprazole hair loss questions, start by identifying your exact hair problem. Use proven hair therapies for pattern or autoimmune loss, fix triggers for shedding, and reserve aripiprazole for specialist‑led care when hair loss stems from hair‑pulling behaviour.